The human–animal bond has evolved and diversi?ed down the ages. Dogs, cats and even horses, have long ful?lled the role of faithful companion and indeed, as exempli?ed by the introduction of seeing and hearing dogs, there may be a critical level of co-dependency between the species. In the twenty-?rst century, the animal types that are kept as pets in many parts of the world are extensive ranging from reptiles through rodents to ruminants and beyond. As would be predicted by the nature of the relationship, the approach to treatment of a companion animal is often closely aligned to that which would have been offered to their owner. However, an increasing awareness of welfare issues, such as the recognition that animals expe- ence pain and the proven bene?ts of disease prevention in intensive farming units, together with the growth in zoos and wildlife parks, has increased the likelihood of food producing and non-domesticated animals receiving medicinal products during their life-time. Although many of the individual drugs or classes of drugs administered to animals are the same as, or derived from, those given to man, the safe and effective use of drugs in animals often cannot be achieved by simply transposing knowledge of drug action on, or behaviour in, the body from one species to another. The impact of the anatomical, physiological and pathophysiological variability that spans the animal kingdom can often profoundly alter drug response.

Although usually treated as unified subject, in many respects the two components of what is broadly described as 'medical and veterinary is usual, the term entomology is entomology' are clearly distinct. As used loosely here to refer to both insects and arachnids. In medical entomology blood-feeding Diptera are of paramount importance, primarily as vectors of pathogenic disease. Most existing textbooks reflect this bias. However, in veterinary entomology ectoparasites such as the mites, fleas or dipteran agents of myiasis assume far greater prominence and the most important effects of their parasitic activity may be mechanical damage, pruritus, blood loss, myiasis, hypersensitivity and dermatitis, in addition to vector-borne pathogenic disease. Ectoparasite infestation of domestic and companion animals, therefore, has clinical consequences necessitating a distinct approach to diagnosis and control. The aim of this book is to introduce the behaviour, ecology, pathology and control of arthropod ectoparasites of domestic animals to students and practitioners of veterinary medicine, animal husbandry and applied biology. Since the book is directed primarily at the non-entomologist, some simplification of a number of the more involved entomological issues has been deemed necessary to improve the book's logical structure and comprehensibility, and keep its length within limits. A reading list is presented at the end of each chapter to act as a stepping-stone into the specialist literature.

This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

This book highlights the state of the field in the new, provocative line of research into the cognition and behavior of the domestic dog. Eleven chapters from leading researchers describe innovative methods from comparative psychology, ethology and behavioral biology, which are combined to create a more comprehensive picture of the behavior of Canis familiaris than ever before. Each of the book’s three parts highlights one of the perspectives relevant to providing a full understanding of the dog. Part I covers the perceptual abilities of dogs and the effect of interbreeding. Part II includes observational and experimental results from studies of social cognition – such as learning and social referencing – and physical cognition in canids, while Part III summarizes the work in the field to date, reviewing various conceptual and methodological approaches and testing anthropomorphisms with regard to dogs. The final chapter discusses the practical application of behavioral and cognitive results to promote animal welfare. This volume reflects a modern shift in science toward considering and studying domestic dogs for their own sake, not only insofar as they reflect back on human beings.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry. Such technologies offer beneficial advantages to the veterinarian, farmer and pet owner. These advantages have resulted in them growing in popularity in recent years. The pharmaceutical scientist is faced with many challenges when innovating new products in this demanding field of controlled release. This book provides the reader with a comprehensive guide on the theories, applications, and challenges associated with the design and development of long acting veterinary formulations. The authoritative chapters of the book are written by some of the leading experts in the field. The book covers a wide scope of areas including the market influences, preformulation, biopharmaceutics, in vitro drug release testing and specification setting to name but a few. It also provides a detailed overview of the major technological advances made in this area. As a result this book covers everything a formulation scientist in industry or academia, or a student needs to know about this unique drug delivery field to advance health, production and reproduction treatment options and benefits for animals worldwide.

Small-Animal SPECT Imaging is an edited work derived from the first workshop on Small-Animal SPECT Imaging held January 14-16, 2004 at the University of Arizona, Tucson, AZ, USA. The overall goal of the meeting and therefore this volume is to promote information exchange and collaboration between the research groups developing systems for small-animal applications. Topics include the biomedical significance of small-animal imaging, an overview of detector technologies including scintillation cameras and semi-conductor arrays, imager design and data acquisition systems, animal handling and anesthesia issues, objective assessment of image quality, and system modeling and reconstruction algorithms.